Photiosity2 is a Mac-only application to sharpen blurred photos. The program tries to estimate the type and size of the blur (point spread function) in order to determine the original sharp image.
It works only with Mavericks (OS X 10.9). You can download a tryout-version of Photiosity2 here!  


Photiosity2 in action on a very slow 2010-MacBook-Pro...: